Figure 7.

The four clusters of amyotrophic lateral sclerosis (ALS) patients, based on the average mismatch negativity (MMN) delay (short, above normal, long, and extra-long delays), showing moderate relationship with Stroop Color–Word Interference task (i.e., cognition), but no overlap with traditionally defined phenotypes, age, gender, ALS Functional Rating Scale (ALSFRS-R), or five main Edinburgh Cognitive and Behavioural ALS Screen (ECAS) scores. The four subgroups, found through k-mean clustering of the average MMN delay are shown against healthy controls.