Table 2.

Values of coagulation parameters, fibrinolysis parameters, and blood cell count.

Coagulation parameters
Group	VEH n = 20	100 mg/kg n = 15	200 mg/kg n = 18	400 mg/kg n = 21
PT [s]	12.04 ± 0.60	12.31 ± 0.40	12.88 ± 0.20	12.02 ± 0.40
QUICK [%]	94.7 ± 3.3	90.3 ± 2.5	86.3 ± 1.2	93.6 ± 3
INR	1.10 ± 0.10	1.10 ± 0.03	1.16 ± 0.02	1.08 ± 0.03
Fibrinogen [g/l]	2.02 ± 0.05	2.25 ± 0.08	2.24 ± 0.20	2.14 ± 0.08
APTT [s]	16.54 ± 0.60	17.56 ± 0.99	16.83 ± 0.48	17.14 ± 0.22
Fibrinolysis parameters
Group	VEH n = 11	100 mg/kg n = 9	200 mg/kg n = 10	400 mg/kg n = 12
PAI-1 total [ng/ml]	1.16 ± 0.10	1.28 ± 0.15	1.10 ± 0.06	1.30 ± 0.11
PAI-1 activity [ng/ml]	1.50 ± 0.22	1.25 ± 0.30	1.29 ± 0.14	1.67 ± 0.23
Blood cell count
Group	VEH n = 20	100 mg/kg n = 13	200 mg/kg n = 21	400 mg/kg n = 22
WBC [103 mm3]	2.8 ± 0.2	3.1 ± 0.4	2.3 ± 0.2	2.9 ± 0.2
RBC [106 mm3]	7.3 ± 0.2	7.3 ± 0.1	7.2 ± 0.9	7.4 ± 0.1
HGB [g/dl]	14.4 ± 0.2	14.3 ± 0.2	14.0 ± 0.3	14.4 ± 0.2
HCT [%]	42.0 ± 0.6	42.0 ± 0.6	41.3 ± 0.8	42.0 ± 0.7
PLT [103 mm3]	557.2 ± 20	572.0 ± 16.9	590.2 ± 14	588.0 ± 17.1
MCV [fl]	57.3 ± 0.3	57.5 ± 0.4	57.5 ± 0.5	56.9 ± 0.4
MCH [pg/cell]	19.9 ± 0.2	19.5 ± 0.1	19.5 ± 0.2	19.5 ± 0.2
MCHC [g/Dl]	34.7 ± 0.3	34.0 ± 0.1	33.8 ± 0.2	34.3 ± 0.3

p = ns. Data are shown as mean ± SEM.