Table 4.

Stratification analysis of association between SNPs in lncRNA-p53 regulatory network genes and the toxic reactions in NPC patients.

Stratified factors	n	SNP	Toxic reactions	OR (95% CI)	P
IC regimen-TP	203	rs2027701	Dermatitis	4.721 (1.141–19.536)	0.032
		rs73594404	Leukopenia	3.394 (1.263–9.123)	0.015
			Myelosuppression	3.054 (1.178–7.922)	0.022
IC regimen-DP	200	rs1059698	Mucositis	0.527 (0.279–0.997)	0.049
		rs10132552	Leukopenia	4.300 (1.345–13.748)	0.014
			Neutropenia	5.462 (1.836–16.251)	0.002
		rs73594404	Thrombocytopenia	3.540 (1.089–11.500)	0.036
Sex-Female	131	rs2027701	Mucositis	3.375 (1.025–11.108)	0.045
		rs73594404	Thrombocytopenia	10.237 (2.530–41.429)	0.001
		rs10132552	Myelosuppression	4.135 (1.303–13.119)	0.016
CCRT regimen-TP	108	rs73594404	Leukopenia	3.784 (1.086–13.184)	0.037

Abbreviations: OR, odds ratio; CI, confidence interval;

P value < 0.05 is shown in bold.