Table 3.

Accuracy estimates for subgroup analyses.

Factor	Subgroups	Imaging	No	pSEN (95% CI)	pSPE (95% CI)	AUC (95% CI)
Cut-off value	ROC analysis	MRI	9	0.80 (0.73–0.86)	0.80 (0.75–0.84)	0.86 (0.83–0.89)
		PET/CT	9	0.74 (0.66–0.81)	0.88 (0.84–0.91)	0.92 (0.90–0.94)
				P = 0.313	P = 0.123	P = 0.124
	Pre-specified	MRI	5	0.61 (0.39–0.79)	0.83 (0.54–0.95)	0.73 (0.69–0.76)
		PET/CT	5	0.79 (0.65–0.89)	0.81 (0.75–0.86)	0.87 (0.82–0.92)
				P = 0.005*	P = 0.713	P = 0.022*
MRI modality	Conventional CE-MRI	MRI	9	0.74 (0.60–0.85)	0.82 (0.71–0.89)	0.84 (0.81–0.87)
		PET/CT	9	0.88 (0.71–0.95)	0.82 (0.65–0.92)	0.92 (0.89–0.94)
				P = 0.018*	P = 0.999	P = 0.104
	Functional MRI	MRI	4	0.87 (0.49–0.98)	0.82 (0.67–0.89)	0.89 (0.86–0.91)
		PET/CT	4	0.78 (0.52–0.92)	0.92 (0.82–0.98)	0.93 (0.90–0.95)
				P = 0.060	P = 0.057	P = 0.258
Evaluation time	Early evaluation	MRI	4	0.73 (0.53–0.87)	0.83 (0.64–0.93)	0.85 (0.81–0.88)
		PET/CT	4	0.71 (0.35–0.92)	0.94 (0.78–0.98)	0.92 (0.89–0.94)
				P = 0.753	P = 0.015*	P = 0.163
	Post evaluation	MRI	5	0.85 (0.68–0.94)	0.83 (0.70–0.92)	0.91 (0.88–0.93)
		PET/CT	5	0.89 (0.77–0.96)	0.80 (0.53–0.93)	0.90 (0.87–0.93)
				P = 0.400	P = 0.585	P = 0.798

pSEN = pooled sensitivities; pSPE = pooled specificities; *P < 0.05.