Table 1.
Genes differentially expressed in antibody-treated versus untreated BT474 cell
| Genes | GenBank Accession# | Ratio* |
| Extracellular matrix remodeling: | ||
| COL11 | J04177 | - 6.2 |
| MMP17 | X89576 | - 4.7 |
| MMP16 | D50477 | -4.6 |
| SPARC | J03040 | 5.7 |
| Adhesion: | ||
| PKD1 | U24497 | - 7.3 |
| NCAM | AF002246 | 7.3 |
| M-cadherin | D83542 | 3.5 |
| Cytoskeleton plasticity: | ||
| SPTA1 | M61877 | 7.4 |
| Signal transduction: | ||
| RGS4 | U27768 | - 10.1 |
| GAS | L13720 | - 7.1 |
| BMP1 | U50330 | - 7.0 |
| FGFR4 | L03840 | - 6.5 |
| PMEL17 | M77348 | - 6.5 |
| ETS-1 | - 5.9 | |
| ERBB2 | M95667 | - 5.8 |
| TGF-beta | X02812 | - 5.2 |
| N-ras | X02751 | - 4.8 |
| HRS | D84064 | - 4.7 |
| KIR | U10550 | 9.0 |
| BMP6 | M60315 | 7.5 |
| BIN1 | U68485 | 7.4 |
| SGI | Y00064 | 4.1 |
| CDC7 | AF015592 | 3.8 |
| CNTF | S72921 | 3.4 |
| SH3BP2 | AF000936 | 3.1 |
| Apoptosis: | ||
| CD27BP | U82938 | 6.0 |
| DR5 | F016268 | 4.8 |
| Metabolism: | ||
| PPAT | U00238 | 6.3 |
| HPRT | P00492 | 5.4 |
| Immune response: | ||
| MHC class I | U65416 | 8.4 |
| Replication/repair/transcription: | ||
| CHAF1A | U20979 | - 12.3 |
| NEK3 | Z29067 | - 5.6 |
| BTG | U72649 | 8.9 |
| HRC1 | M91083 | 6.2 |
| TOP1 | J03250 | 4.9 |
| CLK1 | L29222 | 4.0 |
| Functionally unclassified | ||
| PIG7 | AF010312 | - 4.9 |
| menin | U93236 | 3.1 |
*Ratio of normalized data from antibody-treated versus untreated BT474 cells as described in the Materials and Methods section. Negative values indicate downregulated and positive values upregulated genes.