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. 2017 Aug 16;7:8480. doi: 10.1038/s41598-017-09095-3

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The expression of the PRKAA1 mRNA was regulated by miR-181a during the formation of CFC- and OLT-dependent memories. (a) qPCR analysis showing the relative levels of PRKAA1 expression in the mouse DH 2 h after CFC training. **p < 0.01, compared with the naïve group. ^## p < 0.01, compared with the CFC + antagomir control group. (b) Relative levels of PRKAA1 expression in the mouse DH 2 h after OLT training. **p < 0.01, compared with the naïve group. ^## p < 0.01, compared with the CFC + antagomir control group. n = 5 per group. All values are presented as means ± SEM.