Table 1.
WT | CD2AP-KO (3-week old) | |
---|---|---|
Slit pores | ||
Number of pores/μm FP | 27.44 | 20.68 |
Slit gaps | ||
Number of slit gaps/FP | 0/101 | 4/60 |
Length of FP (nm) | 1654 ± 79 | 460 ± 29 |
FP, foot process. The number of slit pores are analyzed in WT (7.47 μm of FP length) and 3 week-old Cd2ap-KO (11.94 μm of FP length) mice. We defined “slit gap” as occurring when three or more consecutive cross-bridging filaments separating slit pores are broken. Length of FP is measured in WT (n = 30) and 3 week-old Cd2ap-KO (n = 24) mice, and presented as means ± standard error of the mean, SEM.