Table 2.
Univariate Cox analysis for factors potentially influence survival outcomes.
| Characteristic | PFS | OS | ||||
|---|---|---|---|---|---|---|
| p* | HR | 95%CI | p* | HR | 95%CI | |
| Age ≥ 50 | 0.039 | 1.619 | 1.024–2.560 | 0.014 | 1.798 | 1.125–2.874 |
| KPS < 80 | 0.015 | 1.766 | 1.115–2.796 | 0.005 | 1.998 | 1.233–3.237 |
| Volume ≥ 50 (cm3) | 0.250 | 1.299 | 0.832–2.027 | 0.227 | 1.326 | 0.839–2.094 |
| < GTR | 0.031 | 1.631 | 1.046–2.544 | 0.003 | 2.035 | 1.283–3.227 |
| RT plus TMZ | 0.266 | 0.672 | 0.333–1.354 | 0.267 | 0.658 | 0.315–1.377 |
| FD < 1.56 | 0.006 | 1.933 | 1.209–3.091 | 0.008 | 1.919 | 1.182–3.117 |
| Lacunarity > 0.46 | 0.012 | 1.774 | 1.133–2.777 | 0.005 | 1.935 | 1.220–3.068 |
Abbreviations: CI, confidence interval; HR, hazard ratio; RT, radiotherapy; TMZ, temozolomide; *without Bonferroni correction.