Table 4.
The detected QTL and the most significant SNP for female fertility traits in the meta-analysis across populations.
| QTL boundaries | Most significant SNP1 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| BTA | Trait1 | Left2 (bp) | Right3 (bp) | N4 | Position5 (bp) | SNP | MAF6 | P-value | Genes7 |
| 1 | CRc | 78,034,231 | 78,511,271 | 1 | 78,034,231 | rs29009958 | 0.35, 0.41 | 3.92E-06 | TP63 |
| 13 | IFLc | 31,524,626 | 31,524,626 | 1 | 31,524,626 | rs41604666 | 0.49, 0.48 | 3.67E-06 | RSU1 |
| 17 | CRh | 67,245,920 | 67,941,337 | 2 | 67,245,920 | rs41848120 | 0.48, 0.46 | 2.54E-06 | PIWIL3, MYO18B |
| 23 | CRc | 49,651,909 | 50,036,208 | 1 | 50,036,208 | rs110076231 | 0.38, 0.45 | 4.79E-05 | PRPF4B, PXDC1 |
| 28 | ICF | 34,021,273 | 34,596,949 | 1 | 34,429,786 | rs110181893 | 0.29, 0.42 | 5.22E-05 | ENSBTAG00000013264, ZMIZ1 |
1CRh = conception rate at first insemination in heifers; ICF = interval from calving to first insemination; IFLc = interval from first to last insemination in cows; CRc = conception rate at first insemination in cows.
2The left boundary of the QTL.
3The right boundary of the QTL.
4The number of significant SNPs within the QTL.
5The base pair position in the BTA (Bos taurus autosome).
6Minor allele frequency of the most significant SNP in Chinese and Nordic Holsteins.
7Genes harbor or closest to the most significant SNP.