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. 2017 Aug 15;8(4):e01186-17. doi: 10.1128/mBio.01186-17

TABLE 2 .

SIV DNA and RNA levels in two brain regions (basal ganglia and parietal cortex) at terminal point and number of latently infected BrMΦ for each macaquea

Cohort and animal identifier No. of SIV DNA copies per 106 cells
No. of SIV RNA copies per µg RNA
Brain MΦ-QVOA IUPM
Basal ganglia Parietal cortex Basal ganglia Parietal cortex Without wells (<50 copies/ml) With wells (<50 copies/ml)
A1
    PmA11 <10 <10 <10 <10 0.147 0.917
    PmA12 <10 <10 <10 <10 0.036 0.230
    PmA13 <10 64 <10 <10 0.036 0.110
A2
    PmA21 <10 <10 <10 <10 1.445 1.445
    PmA22 <10 <10 <10 <10 0.177 1.309
    PmA23 <10 <10 <10 <10 7.362 7.362
    PmA24 <10 <10 <10 <10 <0.021 <0.021
    PmA25 <10 <10 <10 <10 0.613 0.613
a

QVOA values are presented and represent the presence or absence of positive wells with fewer than 50 SIV RNA copies/ml of supernatant. Values reflect maximum likelihood estimates of infection frequency in IUPM (infectious units per million cells). Given the resolution of the assay, the 95% confidence interval is typically 0.2 to 4 times the reported value.