TABLE 2 .
SIV DNA and RNA levels in two brain regions (basal ganglia and parietal cortex) at terminal point and number of latently infected BrMΦ for each macaquea
| Cohort and animal identifier | No. of SIV DNA copies per 106 cells |
No. of SIV RNA copies per µg RNA |
Brain MΦ-QVOA IUPM |
|||
|---|---|---|---|---|---|---|
| Basal ganglia | Parietal cortex | Basal ganglia | Parietal cortex | Without wells (<50 copies/ml) | With wells (<50 copies/ml) | |
| A1 | ||||||
| PmA11 | <10 | <10 | <10 | <10 | 0.147 | 0.917 |
| PmA12 | <10 | <10 | <10 | <10 | 0.036 | 0.230 |
| PmA13 | <10 | 64 | <10 | <10 | 0.036 | 0.110 |
| A2 | ||||||
| PmA21 | <10 | <10 | <10 | <10 | 1.445 | 1.445 |
| PmA22 | <10 | <10 | <10 | <10 | 0.177 | 1.309 |
| PmA23 | <10 | <10 | <10 | <10 | 7.362 | 7.362 |
| PmA24 | <10 | <10 | <10 | <10 | <0.021 | <0.021 |
| PmA25 | <10 | <10 | <10 | <10 | 0.613 | 0.613 |
QVOA values are presented and represent the presence or absence of positive wells with fewer than 50 SIV RNA copies/ml of supernatant. Values reflect maximum likelihood estimates of infection frequency in IUPM (infectious units per million cells). Given the resolution of the assay, the 95% confidence interval is typically 0.2 to 4 times the reported value.