Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Aug 16;37(33):7824–7836. doi: 10.1523/JNEUROSCI.0691-17.2017

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 Wegner et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

PMC Copyright notice

Figure 3. — The hyperpolarized state of Fbxl3^Afh/Afh vSCN neurons was sustained during the circadian night. A, Examples of wheel-running activity (WRA) rhythms of Fbxl3^+/+ (+/+) and Fbxl3^Afh/Afh (Afh/Afh) mice in constant dark. WRA: CT12 = activity onset (black arrows). Circadian times of recorded cells were adjusted according to the circadian period of individual animals as calculated from activity onsets. The circadian period in WRA was lengthened by the Afh mutation (B), whereas rhythm strength was diminished (C). During circadian night, RMP was reduced by the Afh mutation (D), whereas spontaneous firing rate was slightly damped (E). Data in B–E are plotted as mean ± SEM. *p < 0.05, ***p < 0.001.