Histologic patterns of pneumonitis associated with anti–programmed death-1/programmed death ligand 1 therapy on lung biopsy (hematoxylin and eosin [HE] stain magnification, ×200) included (A) cellular interstitial pneumonitis (mild case shown), (B) organizing pneumonia, and (C) diffuse alveolar damage. Additional findings (HE stain magnification, ×400) include (D) poorly formed granulomas, and (E) eosinophils (arrows).