Table 2.
Level of evidence (GRADE).
| Outcome | Effect | Number of participants | Quality of the evidence | |
|---|---|---|---|---|
| Relative effect (95% CI) | Absolute effect (95% CI) | (studies) | (GRADE) | |
| Harris hip score | MD 11.52 higher (10.05 to 12.99 higher) |
241 (6 studies) |
⊕⊕OO Low1,2 |
|
|
| ||||
| Necrotic area of femoral head | MD 5.65 higher (7.15 to 4.16 higher) |
146 (4 studies) |
⊕⊕OO Low1,2 |
|
|
| ||||
| Collapse of the femoral head | OR 0.23 (0.12 to 0.47) |
136 fewer per 1000 (from 89 more to 1599 more) |
425 (9 studies) |
⊕⊕OO Low1,2 |
|
| ||||
| Conversion to THR | OR 0.29 (0.13 to 0.62) |
112 fewer per 1000 (from 56 more to 141 more) |
380 (7 studies) |
⊕⊕OO Low1,2 |
1 Most of them did not mention randomization process, allocation concealment, and blinding; 2 published evidence is limited due to a small number of trials, all of which are showing benefits.