Table 2.
Allele frequency of SNPs associated with BMD phenotypes in the discovery sample and comparison with other populations.
| Minor allele frequency | ||||||
|---|---|---|---|---|---|---|
| SNP | CHR | Gene | CEUa | MXLa | MXb | AMRc |
| rs1432910 | 5 | SLIT3 | 0.56 | 0.44 | 0.48 | 0.58 |
| rs2278391 | 5 | SLIT3 | 0.16 | 0.24 | 0.27 | 0.39 |
| rs6904364 | 6 | RMND1 | 0.37 | 0.41 | 0.38 | 0.36 |
| rs17081341 | 6 | CCDC170 | 0.03 | 0.16 | 0.17 | 0.24 |
| rs11764843 | 7 | HDAC9 | 0.65 | 0.48 | 0.49 | — |
| rs17413103 | 7 | SHFM1 | 0.09 | 0.09 | 0.11 | 0.11 |
— means information not available for this SNP; CEU: Utah residents with Northern and Western European ancestry; MXL: Mexican Ancestry in Los Angeles, California. aData obtained from 1000 Genomes dataset. bMX: Mexican-Mestizo population from Central México (Morelos state). cAMR: Amerindian population of Nahua, Totonac, and Zapotec. Data were obtained from Consortium for the Study of Genomic Diversity of the Indigenous Populations.