Table 1.
Clinicopathologial Characterisics of patients with ccRCC in TCGA and FUSCC cohort
| Variables | TCGA cohort(N=509) | FUSCC cohort(N=178) | p1 | ||
|---|---|---|---|---|---|
| N | % | N | % | ||
| Age, median(range) | 61(26 to 90) | 56(25 to 86) | <0.0012 | ||
| Gender | 0.360 | ||||
| Male | 328 | 64.4 | 122 | 68.5 | |
| Female | 181 | 35.6 | 56 | 31.5 | |
| Tumor size, mean(range) | 1.68(0.4 to 4.0) | 5.00(1.0 to 16.0) | <0.0012 | ||
| Laterality | 0.270 | ||||
| Left | 239 | 47 | 82 | 46.1 | |
| Right | 269 | 52.8 | 94 | 52.8 | |
| bilateral | 1 | 0.2 | 2 | 1.1 | |
| Grade | 0.051 | ||||
| 1 | 12 | 2.4 | 9 | 5.1 | |
| 2 | 222 | 43.6 | 72 | 40.4 | |
| 3 | 197 | 38.7 | 81 | 45.5 | |
| 4 | 74 | 14.5 | 16 | 9 | |
| Gx | 4 | 0.8 | 0 | 0 | |
| pT | <0.001 | ||||
| T1 | 258 | 50.7 | 126 | 70.8 | |
| T2 | 63 | 12.4 | 23 | 12.9 | |
| T3 | 178 | 35 | 25 | 14 | |
| T4 | 10 | 2 | 4 | 2.2 | |
| N | <0.001 | ||||
| N0 | 228 | 44.8 | 169 | 94.9 | |
| N1 | 17 | 3.3 | 2 | 1.1 | |
| Nx | 264 | 51.9 | 7 | 3.9 | |
| M | <0.001 | ||||
| M0 | 406 | 79.8 | 171 | 96.1 | |
| M1 | 78 | 15.3 | 6 | 3.4 | |
| Mx | 25 | 4.9 | 1 | 0.6 | |
| Stage | <0.001 | ||||
| I | 253 | 49.7 | 125 | 70.2 | |
| II | 51 | 10 | 20 | 11.2 | |
| III | 125 | 24.6 | 25 | 14 | |
| IV | 80 | 15.7 | 8 | 4.5 | |
1 χ2 test or indicated otherwise.
2 t test.
TCGA, The Cancer Genome Atlas; FUSCC, Fudan University Shanghai Cancer Center