Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Spliced exons within an intron suppress splicing. (A) Schematic of the double duplication construct and its derivatives. (B) Spliced pre-mRNAs synthesized with T7 RNA polymerase. (C) Coupled transcription splicing system. Shaded boxes indicate full-length exon 1, and white boxes indicate full-length exon 2. Ovals indicate the position of the lariat exon intermediate or the excised intron. Coiled lines indicate a size-matched random sequence.
