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. Author manuscript; available in PMC: 2017 Aug 17.
Published in final edited form as: Nat Genet. 2016 Jul 25;48(9):1037–1042. doi: 10.1038/ng.3626

Figure 2.

Figure 2

Replication analysis of NEK1 p.Arg261His. NEK1 p.Arg261His genotypes were ascertained for 1,022 FALS samples, 6,172 SALS samples and 11,732 controls. The SALS cohort was divided into seven geographically based case–control strata. Logistic regression was used to conduct tests of allelic association for all subcohorts and was followed by a fixed-effects meta-analysis. In the distribution of OR estimates across study cohorts (right), vertical dotted line denotes OR estimated under meta-analysis. CI, confidence interval.