Table 2. Prediction of accelerated vBMD loss (defined as being in the upper quartile of annual % bone loss) of femoral neck and total hip by BTM in women.
| vBMD loss | Model | CTX | OC | PINP | |||
|---|---|---|---|---|---|---|---|
|
|
|
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| OR | 95% CI | OR | 95% CI | OR | 95% CI | ||
| Femoral neck | |||||||
| Trabecular (-14.3 to 3.4 %) | 1 | 1.44 | 0.94-2.20 | 1.94 | 1.27-2.96 | 1.35 | 0.89-2.06 |
| 2 | 1.49 | 0.94-2.34 | 2.30 | 1.44-3.70 | 1.45 | 0.92-2.28 | |
| Cortical (-6.5 to -0.4 %) | 1 | 1.98 | 1.31-2.99 | 2.44 | 1.61-3.70 | 2.08 | 1.38-3.13 |
| 2 | 1.76 | 1.13-2.75 | 2.20 | 1.39-3.48 | 1.89 | 1.22-2.92 | |
| Total hip | |||||||
| Trabecular (-7.6 to -2.5 %) | 1 | 1.16 | 0.75-1.80 | 1.73 | 1.13-2.66 | 1.52 | 1.00-2.32 |
| 2 | 1.23 | 0.77-1.97 | 2.02 | 1.25-3.27 | 1.71 | 1.09-2.69 | |
| Cortical (-3.6 to -0.4 %) | 1 | 1.70 | 1.12-2.59 | 2.00 | 1.31-3.04 | 1.63 | 1.08-2.47 |
| 2 | 1.57 | 1.01-2.47 | 1.94 | 1.22-3.08 | 1.48 | 0.95-2.30 | |
Data are presented as odds ratios (95% CI) and are bold if p< 0.05 for the highest quartile of BTM levels (CTX ≥0.50, OC ≥31.80, and PINP ≥47.95) calculated by logistic regression; Model 1 - adjusted for age; Model 2 - adjusted for age, BMI, smoking, alcohol consumption, physical activity level, mobility disability, serum 25OHD, PTH, follow-up duration, DM, Oral glucocorticoid or antiepileptic drugs, anti-bone loss drugs, and age at menopause.