Table 3. Prediction of accelerated vBMD loss (defined as being in the upper quartile of annual % bone loss) of femoral neck and total hip by BTM in men.
vBMD loss | Model | CTX | OC | PINP | |||
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|
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OR | 95% CI | OR | 95% CI | OR | 95% CI | ||
Femoral neck | |||||||
Trabecular (-12.1 to -2.6 %) | 1 | 1.42 | 0.89-2.28 | 1.25 | 0.78-2.02 | 1.47 | 0.92-2.35 |
2 | 1.43 | 0.88-2.32 | 1.25 | 0.76-2.05 | 1.44 | 0.89-2.34 | |
Cortical (-6.4 to -0.3 %) | 1 | 1.34 | 0.83-2.15 | 1.88 | 1.18-2.98 | 1.75 | 1.10-2.78 |
2 | 1.29 | 0.79-2.10 | 1.84 | 1.13-2.99 | 1.68 | 1.04-2.72 | |
Total hip | |||||||
Trabecular (-7.7 to -1.7 %) | 1 | 2.32 | 1.47-3.67 | 2.70 | 1.71-4.28 | 2.26 | 1.43-3.58 |
2 | 2.41 | 1.50-3.89 | 2.84 | 1.75-4.61 | 2.26 | 1.40-3.63 | |
Cortical (-3.4 to -0.3 %) | 1 | 2.17 | 1.37-3.44 | 2.43 | 1.53-3.86 | 2.52 | 1.59-3.99 |
2 | 2.24 | 1.38-3.63 | 2.45 | 1.51-3.99 | 2.50 | 1.55-4.03 |
Data are presented as odds ratios (95% CI) and are bold if p< 0.05 for the highest quartile of BTM levels (CTX ≥0.472, OC ≥26.94, and PINP ≥41.90) calculated by logistic regression; Model 1 - adjusted for age; Model 2 - adjusted for age, BMI, smoking, alcohol consumption, physical activity level, mobility disability, serum 25OHD, PTH, follow-up duration, DM, Oral glucocorticoid or antiepileptic drugs, and anti-bone loss drugs.