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. Author manuscript; available in PMC: 2017 Aug 17.
Published in final edited form as: Osteoporos Int. 2016 Jun 24;27(12):3485–3494. doi: 10.1007/s00198-016-3675-7

Table 3. Prediction of accelerated vBMD loss (defined as being in the upper quartile of annual % bone loss) of femoral neck and total hip by BTM in men.

vBMD loss Model CTX OC PINP



OR 95% CI OR 95% CI OR 95% CI
Femoral neck
 Trabecular (-12.1 to -2.6 %) 1 1.42 0.89-2.28 1.25 0.78-2.02 1.47 0.92-2.35
2 1.43 0.88-2.32 1.25 0.76-2.05 1.44 0.89-2.34
 Cortical (-6.4 to -0.3 %) 1 1.34 0.83-2.15 1.88 1.18-2.98 1.75 1.10-2.78
2 1.29 0.79-2.10 1.84 1.13-2.99 1.68 1.04-2.72
Total hip
 Trabecular (-7.7 to -1.7 %) 1 2.32 1.47-3.67 2.70 1.71-4.28 2.26 1.43-3.58
2 2.41 1.50-3.89 2.84 1.75-4.61 2.26 1.40-3.63
 Cortical (-3.4 to -0.3 %) 1 2.17 1.37-3.44 2.43 1.53-3.86 2.52 1.59-3.99
2 2.24 1.38-3.63 2.45 1.51-3.99 2.50 1.55-4.03

Data are presented as odds ratios (95% CI) and are bold if p< 0.05 for the highest quartile of BTM levels (CTX ≥0.472, OC ≥26.94, and PINP ≥41.90) calculated by logistic regression; Model 1 - adjusted for age; Model 2 - adjusted for age, BMI, smoking, alcohol consumption, physical activity level, mobility disability, serum 25OHD, PTH, follow-up duration, DM, Oral glucocorticoid or antiepileptic drugs, and anti-bone loss drugs.