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. 2017 Aug 1;10(8):981–991. doi: 10.1242/dmm.030080

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© 2017. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 1. — Measures of locomotor activity, motor coordination and balance. Measures of locomotor activity in the PhenoMaster cages (females: A, males: B), open field (C) and voluntary running wheels (females D, males E), and motor coordination and balance in the rotarod (F; seconds). *P<0.05 vs +/+ controls. (B,D) Boxes indicate an increase in activity just after lights on in the rest phase seen in female +/− mice in voluntary running wheels (D) and in male +/− mice in home-cage activity (B). The cohort included 21 female (9 +/− and 12 +/+) and 23 male (10 +/− and 13 +/+) mice. Results are plotted as means±s.e.m. rev, revolutions.