Table 1.
Demographic, morphometric, and cognitive characterisation of the sample enrolled in this study.
| Variable | Mean | SD | Median | Minimum | Maximum |
|---|---|---|---|---|---|
| Demographic features | |||||
| Age (years) | 61.98 | 16.42 | 63.00 | 26.00 | 100.00 |
| Education (years) | 14.88 | 3.19 | 15.00 | 10.00 | 22.00 |
| Subcortical damage | |||||
| WMH load (ml) | 3.26 | 5.83 | 0.82 | 0.00 | 32.58 |
| Global neurostructural indices | |||||
| Grey matter volume (ml) | 636.28 | 67.20 | 633.01 | 446.74 | 752.21 |
| White matter volume (ml) | 415.07 | 44.29 | 408.88 | 337.43 | 527.50 |
| Total intracranial volume (ml) | 1457.69 | 157.06 | 1439.66 | 1217.24 | 1855.43 |
| Grey matter fraction | 0.44 | 0.06 | 0.45 | 0.33 | 0.56 |
| White matter fraction | 0.29 | 0.02 | 0.29 | 0.22 | 0.34 |
| Cognitive scores | |||||
| WAIS—similarities | 24.96 | 4.17 | 26.00 | 15.00 | 32.00 |
| Prose Memory test—immediate recall | 15.98 | 3.52 | 16.00 | 9.00 | 24.00 |
| Prose Memory test—delayed recall | 19.20 | 2.76 | 19.00 | 14.00 | 25.00 |
| Rey-Osterrieth complex figure—copy | 32.23 | 2.96 | 33.00 | 23.00 | 36.00 |
| Rey-Osterrieth complex figure—recall | 15.95 | 4.83 | 16.00 | 7.00 | 27.00 |
| Letter Fluency test | 47.18 | 13.25 | 47.00 | 16.00 | 75.00 |
| Stroop test—time interference (s) | 20.89 | 14.22 | 16.50 | 3.00 | 84.00 |
| Trail-Making test—part B minus part A (s) | 37.75 | 33.74 | 30.00 | 0.00 | 223.00 |
One participant did not complete the Stroop test because of colour blindness. One participant, aged 100 years, did not complete the Rey-Osterrieth complex figure, the Stroop test, or the Trail-Making test because of significant macular pathology. SD: standard deviation.