Table 2.
Multivariable analysis for 12-month local tumor-free recurrence rate
Multivariable analysis for local control rate
| Variable | Comparators | HR (95% CI) | P Value |
|---|---|---|---|
| Treatment | SRS vs. OBS | 0.5 (0.3, 1.0) | 0.041 |
| Primary cancer histologic type | Lung vs. breast | 0.9 (0.3, 2.6) | 0.82 |
| Melanoma vs. breast | 0.7 (0.3, 2.1) | 0.56 | |
| Other vs. breast | 1.2 (0.5, 2.6) | 0.73 | |
| Systemic disease status | Progressing vs. NED/PR | 0.6 (0.3, 1.2) | 0.15 |
| Stable vs. NED/PR | 0.8 (0.4, 1.6) | 0.45 | |
| GPA score | 2.5–3.0 vs. 1.0–2.0 | 1.3 (0.6, 2.5) | 0.52 |
| 3.5–4.0 vs. 1.0–2.0 | 1.1 (0.5, 2.6) | 0.82 | |
| Number of metastases | 2 vs. 1 | 0.8 (0.4,1.8) | 0.59 |
| 3 vs. 1 | 0.9 (0.3, 2.6) | 0.90 | |
| Size of brain metastases | >2.5–3.5 cm vs. 0–2.5 cm | 6.7 (2.0, 23) | 0.0021 |
| >3.5 vs. 0–2.5 | 6.6 (1.9, 23) | 0.0032 |
NED: no evidence of disease, PR: Partial Response