Table 2.
Spatial analysis of the diffusion parameters (FA and ADC) within the CST.
| Parameter/location | Affected hemisphere |
Healthy hemisphere |
Interhemispheric ratio (aff./heal.) |
p-Value | ||
|---|---|---|---|---|---|---|
| Absolute | Relative | Absolute | Relative | |||
| FA | ||||||
| Average | 0.46 ± 0.05 | 1 | 0.51 ± 0.04 | 1 | 90% | 0.001 |
| “Cortical” | 0.26 ± 0.09 | 57% | 0.31 ± 0.09 | 61% | 84% | 0.605 |
| Peritumoral | 0.40 ± 0.13 | 87% | 0.46 ± 0.11 | 90% | 87% | 0.036 |
| /edema | 0.34 ± 0.09 | 74% | ||||
| \edema | 0.44 ± 0.14 | 96% | ||||
| Mesencephal | 0.62 ± 0.08 | 135% | 0.62 ± 0.11 | 122% | 100% | 0.988 |
| Pontine | 0.43 ± 0.10 | 93% | 0.47 ± 0.12 | 92% | 91% | 0.154 |
| ADC [10− 4 mm2/s] | ||||||
| Average | 24.47 ± 4.09 | 1 | 23.12 ± 2.36 | 1 | 106% | 0.002 |
| “Cortical” | 21.36 ± 4.75 | 87% | 20.52 ± 3.38 | 89% | 104% | 0.221 |
| Peritumoral | 23.42 ± 5.45 | 96% | 21.80 ± 2.04 | 94% | 107% | 0.001 |
| /edema | 27.32 ± 8.22 | 112% | ||||
| \edema | 22.88 ± 4.46 | 94% | ||||
| Mesencephal | 24.59 ± 6.37 | 100% | 25.55 ± 3.89 | 111% | 96% | 0.441 |
| Pontine | 20.95 ± 4.39 | 86% | 21.89 ± 3.57 | 95% | 96% | 0.339 |
Detailed overview on FA (presented as mean ± SD) and ADC values (presented as median ± IQR) measured in different locations based on specific-FA-based ROI. “Cortical” = most cranial part of the CST. /edema = edema was present within the CST. \edema = edema was not present within the CST. The column of relative values allows to identify easily locations where the corresponding value is higher or lower than in average. An interhemispheric ratio of the absolute values was calculated to analyze differences between the tumorous and the healthy hemisphere in detail. Statistic shows that both the FA and ADC value differs significantly (p < 0.05) at the peritumoral level (and in average) between the hemispheres.