Table 3.

Primary and secondary study outcomes

	Group MP (n = 33)	Group C (n = 28)	p-valuea
Knee-extension strength (Nm/kg body weight), mean (range)
Baseline	1.15 (0.33–2.0)	1.17 (0.33–1.9)
Discharge	0.10 (0.01–0.28)	0.14 (0.01–0.66)
Mean changeb	1.04 (0.22–1.9)	1.02 (0.22–1.6)	0.8
Mean change in %b	–89	–88
Pain during knee-extension strength test, VAS (mm), median (IQR)
Baseline	0 (0–13)	1 (0–16)
Discharge	30 (11–54)	26 (14–51)
Mean changeb	21 (10–47)	23 (8–42)	0.7
Knee circumference (cm), mean (range)
Baseline)	45 (36–57)	43 (36–50)
Discharge	48 (41–62)	47 (41–54)
Mean changeb	3.6 (–1.5 to 6.5)	3.8 (0.8–7.2)	0.7
Mean change in %b	8	9
TUG test (s), mean (range)
Baseline	8.5 (5.0–13)c	8.1 (5.0–11)d
Discharge	24 (9.9–49)c	25 (5.6–63)d
Mean changeb	16 (2.9–40)c	17 (0.6–53)d	0.8
Mean change in %b	183	196
Pain during TUG test, VAS (mm), median (IQR)
Baseline	4 (0–13)c	4 (0–21)d
Discharge	6 (0–29)c	10 (6–29)d
Mean changeb	0 (–7 to 29)c	8 (1–14)d	0.1
CRP (mg/L), median (IQR)
Baseline	2 (1–6)	2 (1–7)	0.7
2 h postoperatively	2 (1–6)	2 (1–6)	0.9
6 h postoperatively	2 (2–6)	3 (1–7)	0.7
24 h postoperatively	33 (21–50)	72 (57–92)	< 0.001
48 h postoperatively	83 (56–125)	192 (147–258)	< 0.001
Rescue morphine equivalents (mg), median (IQR)
baseline to 48 h postoperatively	70 (51–84)c	75 (55–94)	0.5

Nm = Newton meter; IQR = interquartile range

^aindependent-sample t-test or Mann–Whitney U-test (MP versus C)

^bfrom baseline to discharge

^cn = 32

^dn = 27