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. 2016 Jun 23;37(9):881–891. doi: 10.1177/0333102416656118

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© International Headache Society 2016

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — FDG uptake for PET 3 vs PET 1 in compliant MO patients (n = 10). Data were controlled for attack-related modifications. Left: Fronto-temporal metabolism is increased after three months of eTNS treatment (in red: p < 0.001 uncorrected, 20 voxels). The OFC remains significant after correction for multiple comparisons (in blue). Right: First eigenvariate extraction around 10 mm from the peak voxel in the OFC (coordinates obtained from the comparison between PET1 and HVs).

FDG: 18-fluorodeoxyglucose; PET positron emission tomography; MO: migraine without aura; OFC: orbitofrontal cortex; HVs: healthy volunteers.