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Induction of apoptosis in SKOV3 and HeLa cells when treated with CDF, SMA-CDF, and FA-SMA-CDF as evaluated by Annexin V/7-AAD dual staining. An increased percentage of the apoptotic cell population was noted when cells were treated with targeted formulation (FA-SMA-CDF) as compared to both plain CDF and non-targeted SMA-CDF, suggesting the better killing activity of the targeted formulation FA-SMA-CDF (n=3).
