Table 1. Binding of F0016 mAbs to PCSK9 WT and the D374Y variant as determined by SPR.

Antigen	Antibody	ka (1/Ms)	kd (1/s)	KD (M)
PCSK9 WT	F0016A	1.581E+6	2.949E-4	1.866E-10
	F0016B	1.697E+6	2.997E-4	1.765E-10
	F0016C	1.675E+6	3.098E-4	1.850E-10
	F0016D	1.666E+6	3.072E-4	1.843E-10
PCSK9-D374Y	F0016A	2.308E+6	8.095E-4	3.507E-10
	F0016B	2.250E+6	8.062E-4	3.583E-10
	F0016C	2.354E+6	8.071E-4	3.428E-10
	F0016D	2.296E+6	7.863E-4	3.425E-10