Table 3. pH-dependent binding of the F0016 mAbs to FcRn.
Antibody | EC50 (μg/ml) | |
---|---|---|
pH 6.0 | pH 7.4 | |
F0016A | 30.45 ± 0.95 | 45.12 ± 2.11 |
F0016B | 3.47 ± 0.03 | 12.22 ± 0.55 |
F0016C | 1.56 ± 0.02 | 16.49 ± 1.43 |
F0016D | 1.75 ± 0.04 | 8.87 ± 0.59 |
Antibody | EC50 (μg/ml) | |
---|---|---|
pH 6.0 | pH 7.4 | |
F0016A | 30.45 ± 0.95 | 45.12 ± 2.11 |
F0016B | 3.47 ± 0.03 | 12.22 ± 0.55 |
F0016C | 1.56 ± 0.02 | 16.49 ± 1.43 |
F0016D | 1.75 ± 0.04 | 8.87 ± 0.59 |