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. 2017 Aug 17;12(8):e0183326. doi: 10.1371/journal.pone.0183326

Table 3. pH-dependent binding of the F0016 mAbs to FcRn.

EC50 values were calculated using a four-parameter logistic fit regression model. Results were shown as mean ± SD (n = 2).

Antibody EC50 (μg/ml)
pH 6.0 pH 7.4
F0016A 30.45 ± 0.95 45.12 ± 2.11
F0016B 3.47 ± 0.03 12.22 ± 0.55
F0016C 1.56 ± 0.02 16.49 ± 1.43
F0016D 1.75 ± 0.04 8.87 ± 0.59