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DOT maps of concentrations of oxygenated hemoglobin (ctO2Hb), deoxygenated hemoglobin (ctHHb), water, and lipid in the breasts of a human subject with a cancerous tumor in the right breast. The rightmost column is a map of the tissue optical index (TOI), defined by TOI = (ctH2O/Lipid)(ctHHb). The changes in the measured optical parameters correspond well to the tumor region estimated by palpation (black dashed circle) ([6], reproduced with permission).
