Fig 2. Human IgG-specific response against synthetic peptides from S. mansoni targeted for use in diagnosis.

Serum samples were collected from 51 individuals living in an area of low endemicity for S. mansoni infection. Samples from 25 individuals with negative stool examination (NEG) and from 26 individuals with positive stool examination were evaluated (INF). Sera from patients treated 30 and 180 days after treatment were also evaluated. Additionally, sera from 13 healthy donors (HD) not living in an endemic area for schistosomiasis were used as a negative control. Significant differences between groups are indicated in the graphic. Dashed lines represent the cutoff in the absorbance level which determines specificity and sensitivity.