Table 2. Bivariable and multivariable analyses of predictors of CHIK+ status using logistic regression, and the corresponding weighted point values of the score.
Bivariable analysis | Multivariable analysis | Point value | |||||
---|---|---|---|---|---|---|---|
OR | 95% CI | p | OR | 95% CI | p | ||
Fever# | 2.6 | 1.8–3.7 | < .0001 | 2.9 | 1.9–4.6 | < .0001 | 3 |
Arthralgia | 4.3 | 3.0–6.1 | < .0001 | ||||
Arthralgia of the wrist | 3.3 | 1.8–6.2 | .0002 | ||||
Arthralgia of the metacarpophalangeal joints | 2.8 | 1.3–6.5 | < .0001 | ||||
Arthralgia of the ankle# | 2.9 | 1.8–4.8 | < .0001 | 2.3 | 1.2–4.1 | .008 | 2 |
Arthralgia of the knee | 2.8 | 1.8–4.4 | < .0001 | ||||
Arthralgia of the shoulder | 2.7 | 1.3–5.7 | .007 | ||||
Arthralgia of the pelvis | 3.6 | 1.1–12.1 | .04 | ||||
Low back pain | 1.1 | 0.6–1.9 | .77 | ||||
Myalgia | 1.2 | 0.8–1.9 | .32 | ||||
Digestive symptoms | 0.6 | 0.4–0.9 | .02 | ||||
Neurological symptoms | 1.0 | 0.6–1.5 | .94 | ||||
Lymphopenia# | 7.1 | 4.9–10.2 | < .0001 | 6.0 | 3.9–9.1 | < .0001 | 6 |
Absence of neutrophil leukocytosis# | 9.8 | 6.5–14.9 | < .0001 | 10.4 | 6.4–16.9 | < .0001 | 10 |
OR: Odds Ratio; CI: Confidence Interval
# Variables retained in the final multivariable analysis, and therefore, included as components of the score. Point values assigned to each variable included in the score are indicated in the right hand column of the table.