Table 2. Sequence and structural quantification of the three datasets analyzed using the SA-conf tool.
| MTC sets | ||||||||
|---|---|---|---|---|---|---|---|---|
| uPA | P53 | P53-NMR | P53-HMQM | P53-HMQM | PR1 | PR1-NMR | ||
| Number of positions | 261 | 241 | 204 | 195 | 195 | 99 | 99 | |
| All positions | Average neqAA ± sd | 1.02 ± 0.17 | 1.1± 0.22 | - | - | - | 1.09 ± 0.27 | - |
| neqAA maximum value | 2.86 | 2.57 | - | - | - | 3.06 | - | |
| Average neqSL ± sd | 1.66 ± 0.75 | 1.81± 0.95 | 2.69± 2.16 | 1.24 ± 0.41 | 1.25 ± 0.39 | 1.89 ± 0.85 | 1.99 ± 1.04 | |
| neqSL maximum value | 5.08 | 5.58 | 12.76 | 3.14 | 2.40 | 4.47 | 6.23 | |
| Number of conserved positions in terms of AA (neqAA = 1) | 98% (240) | 76% (149) | - | - | - | 84.8% (84) | - | |
| Number of structurally conserved positions (neqSL = 1) | 9% (22) | 14% (27) | 9.5% (19) | 62% (119) | 54.7% (105) | 12.5% (12) | 24% (23) | |
| Number variable regions | 9 | 8 | 7 | 8 | 9 | 8 | 8 | |
| Structurally variable regions | Number of positions (%) | 57 (22%) | 52 (22%) | 115 (56%) | 23 (11%) | 28 (14%) | 43 (43%) | 44 (44%) |
| Average neqAA ± sd | 1 ± 0.008 | 1.06 ± 0.13 | - | - | - | 1.11± 0.34 | - | |
| Average neqSL ± sd | 2.48 ± 0.90 | 2.92 ± 1.05 | 3.43 ± 2.56 | 1.97 ± 0.46 | 1.95 ± 0.28 | 2.55 ± 0.83 | 2.66 ± 1.07 | |