Table 6. Adverse events*.
| Event | N (%) |
|---|---|
| Mental status changes | 10 (45) |
| Somnolence, fatigue | 6 (27) |
| Confusion | 3 (14) |
| Apathy | 2 (9) |
| Polyuria | 1 (5) |
| Leukocytosis | 1 (5) |
| Nausea/vomiting | 2 (9) |
| Reasons for discontinuation of Li+ | |
| Mental status changes | 7 (32) |
| Response | 7 (32) |
| Lack of response | 2 (9) |
| Blistering of skin | 1 (5) |
| Elevated liver function tests | 1 (5) |
| Leukocytosis | 1 (5) |
| Polyuria | 1 (5) |
| Low Li+ serum levels | 1 (5) |
| Change to comfort care | 1 (5) |
*Adverse events observed in patients who received lithium carbonate. No grade 3 toxicity was attributable exclusively to lithium administration.