Table 2. LoB, LoD and LoQ of the five LED based instruments measured on BSA-TSA buffer based TnI samples with TnI assay compared to the current state-of-the art flash lamp based instrument.
BSA-TSA buffer based samplesa | Plasma or WB samples | |||||
---|---|---|---|---|---|---|
Instrument | 1 | 2 | 3 | 4 | 5 | Radiometer AQT90 FLEX [24] |
LoB, ng/L | 0.8 | 0.9 | 1.1 | 0.8 | 1.0 | 4.3 |
LoD, ng/L | 1.5 | 1.9 | 2.1 | 1.9 | 2.0 | 9.5 (plasma) |
LoQ (CV 20%), ng/L | 1.9 | 2.5 | 3.3 | 2.7 | 2.4 | 18 (whole blood) 16 (plasma) |
LoQ (CV 10%), ng/L | 5.8 | 6.9 | 8.4 | 7.3 | 6.8 | 24 (whole blood) 24 (plasma) |
Averaged background value , counts | 204 | 214 | 281 | 195 | 149 | |
Background standard deviation, counts | 19 | 18 | 20 | 15 | 14 |
LOB determined on AB samples