Figure 10. Domain combinations that appear in transcription factor (TF) families in unicellular premetazoans, from the LCA of Unikonta/Amorphea to the LCA of Metazoa.
First and second columns indicate the TF family and its inferred evolutionary origin, respectively (from [de Mendoza et al., 2013]). Subsequent columns list (i) the p-value of a Fisher's exact test for the relative enrichment of that TF family in that node of the tree (compared to other domains that rearrange there; p-values<0.05 in green); and (ii) the accessory domains that appear within each TF family. Figure 7—source data 2, Table 1.
DOI: http://dx.doi.org/10.7554/eLife.26036.036
Figure 10—source data 1. Probability of emergence of protein domain combinations present in the LCA of Metazoa in previous ancestral nodes (from LCA of Metazoa to LCA of Unikonta/Amorphea).
Only protein domain combinations with >90% presence probability in the LCA of Metazoa were included. Protein domain combinations that are not gained with >90% probability in any of the surveyed nodes have been associated with LECA or pre-LECA origins (‘1’ values in the ‘LECA or before’ field). Used in Figure 10.
elife-26036-fig10-data1.xlsx (524.3KB, xlsx)
DOI: 10.7554/eLife.26036.037