Table 3.
Cumulative average | Axon initial segment (AIS) length (µm) | SD | p-Value | PN length (µm) | SD | p-Value |
---|---|---|---|---|---|---|
Subjects (n = 5) | 12.768 | 4.3469 | 0.3328 | 2.9712 | 0.5582 | 0.0769 |
Controls (n = 2) | 11.276 | 0.0834 | n/a | 2.0765 | 0.8831 | n/a |
In the regions adjacent to the microinfarct, AISs were disrupted with a 21.7% increase in average AIS length when compared to control (p = 0.3328). There was no difference in AIS length in the remaining tissue. Paranodal segments were also disrupted with a 30.2% increase in average paranodal length when compared to control (p = 0.0769).