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. 2017 Aug 17;7:8535. doi: 10.1038/s41598-017-08906-x

Figure 1.

Figure 1

Illustration of the randomized-crossover design used in the study. In phase I all six pigs received a single 800 mcg/kg dose of oral ivermectin. After a washout period of 14 days, the animals were randomly assigned to pre-treatment with ketoconazole, rifampicin or nothing in a 1:1:1 ratio and ivermectin dosage and sampling was repeated. The time between ivermectin doses was 30 days. Figure by Juliane Chaccour.