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. 2017 Aug 17;7:8596. doi: 10.1038/s41598-017-08674-8

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The detection limit for the JAK2 V617F and MPL W515K/L mutations in microchambers. Serial dilutions of mutant DNA at concentrations of 100%, 50%, 10%, 1%, 0.1%, 0.01%, 0.001%, and 0% (100% wild-type control) were analyzed by using the microchip-LAMP technique. A: JAK2 V617F; B: MPL W515K; C: MPL W515L.