Table 2.

Linkage of the TOP1MT 256 and 525 alleles.

	V256 homozygous	256 heterozygous	I256 homozygous	total
R525 homozygous	11	25	28	64
525 heterozygous	23	33	0	56
W525 homozygous	9	0	0	9
total	43	58	28	129

^*Source.

129 samples from women with breast cancers were used to genotype TOP1MT variants for both alleles at positions 256 (V or/and I) and 525 (R or/and W).

Chi-square p value = 0.0005.