Table 3.
Differences in the IVIM-DWI parametric values between the pCR and non-pCR groups and between the GR and PR groups.
| Parameter | pCR (n = 10) | non-pCR (n = 32) | P | GR (n = 15) | PR (n = 27) | P |
|---|---|---|---|---|---|---|
| preADC (x10−3 mm2/s) | 1.20 ± 0.18 | 1.25 ± 0.13 | 0.406 | 1.21 ± 0.16 | 1.25 ± 0.13 | 0.503 |
| preD (×10−3 mm2/s) | 0.88 ± 0.13 | 0.91 ± 0.11 | 0.154 | 0.92 ± 0.15 | 0.90 ± 0.09 | 0.937 |
| preD* (×10−3 mm2/s) | 74.64 ± 38.72 | 47.87 ± 31.71 | 0.020* | 60.54 ± 40.47 | 50.74 ± 31.79 | 0.431 |
| pref | 0.21 ± 0.04 | 0.18 ± 0.04 | 0.045* | 0.20 ± 0.04 | 0.18 ± 0.04 | 0.059 |
| postADC (×10−3 mm2/s) | 1.94 ± 0.32 | 1.83 ± 0.37 | 0.423 | 1.93 ± 0.29 | 1.82 ± 0.40 | 0.282 |
| postD (×10−3 mm2/s) | 1.64 ± 0.25 | 1.36 ± 0.24 | 0.004*# | 1.61 ± 0.26 | 1.32 ± 0.22 | 0.002*# |
| postD* (×10−3 mm2/s) | 62.63 ± 42.50 | 46.79 ± 32.16 | 0.192 | 60.72 ± 38.22 | 44.92 ± 32.45 | 0.112 |
| postf | 0.23 ± 0.15 | 0.21 ± 0.07 | 0.805 | 0.22 ± 0.12 | 0.21 ± 0.07 | 0.470 |
| ∆%ADC (%) | 63.19 ± 24.36 | 47.96 ± 32.79 | 0.042* | 60.34 ± 25.05 | 46.72 ± 33.89 | 0.032* |
| ∆%D (%) | 88.51 ± 24.54 | 48.82 ± 22.25 | < 0.001*# | 77.08 ± 27.85 | 47.83 ± 22.91 | 0.001*# |
| ∆%D* (%) | −4.98 ± 54.85 | 60.24 ± 228.51 | 0.738 | 57.91 ± 187.87 | 37.38 ± 208.09 | 0.181 |
*Significance before multiple comparison correction; #significance after multiple comparison correction (P [2] = 0.004 < i*q/m = 2*0.05/12 = 0.0083 for the comparisons between the pCR and non-pCR groups, and P [2] = 0.002 < i*q/m = 2*0.05/12 = 0.0083 for the comparisons between the GR and PR groups) according to the Benjamini- Hochberg procedure21; IVIM-DWI,intravoxel incoherent motion diffusion-weighted imaging; pCR, pathological complete response; non-pCR, non-pathological complete response; GR, good response; PR, poor response; ADC, apparent diffusion coefficient; D, pure diffusion coefficient; D*, pseudo-diffusion coefficient; f, perfusion fraction.