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. 2017 Aug 17;7:8668. doi: 10.1038/s41598-017-09448-y

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Honey bee survival following pinacidil or tolbutamide treatment and infection with 1.5 × 10⁶ pfu of FHV/bee. Data presented as Kaplan-Meier survival curves with points representing mean values ± standard error for 150 bees (6 replicate groups of 25 adult bees). Bees receiving pinacidil experienced significantly lower mortality than untreated bees (Kaplan-Meier log-rank test; P < 0.0001). Bees receiving tolbutamide experienced significantly higher mortality than untreated bees (Kaplan-Meier log-rank test; P < 0.001). Data analyzed using GraphPad Prism 7 software.