FIG 9.

Biosynthetic gene clusters and precursor alignments of class IIc circular bacteriocins identified in non-aureus staphylococci isolated from milk of Canadian dairy cows. (A) Biosynthetic gene clusters of identified class IIc bacteriocins, with inhibiting NAS isolates indicated in boldface and identical precursors in S. gallinarum indicated by asterisks. (B) Alignment of precursor peptides from identified class IIc bacteriocins and known bacteriocins carnocyclin A (accession number B2MVM5), circularin A (accession number Q5L226 [Bactibase accession number BAC164]), enterocin AS-48 (accession number Q47765), gassericin (accession number O24790), and uberolysin (accession number A5H1G9).