TABLE 1.
Species (n) | No. of isolatesa | Group ID |
In vitro inhibition (n) |
No. of bacteriocin gene clusters |
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
S. aureus | MRSAb | Class I |
Class II |
Total | ||||||||
Lanthipeptide | Sactipeptide | Lasso peptide | a | b | c | d | ||||||
S. agnetis (13) | 13 | SAG | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
S. arlettae (15) | 15 | SAR | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
S. auricularis (2) | 2 | SAU | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
S. capitis (22) | 5 | SCAP1 | − | NT | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
5 | SCAP2 | + | + | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |
1 | SCAP3 | − | NT | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 2 | |
1 | SCAP4 | + | + | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | |
1 | SCAP4 | + | − | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 2 | |
7 | SCAP5 | + (7) | + (5) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
2 | SCAP6 | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
S. caprae (1) | 1 | SCAR | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
S. chromogenes (82) | 2 | SCH1 | + | + | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
1 | SCH2 | + | + | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
79 | SCH3 | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
S. cohnii (24) | 2 | SCO1 | − | NT | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
22 | SCO2 | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
S. devriesei (8) | 8 | SDE | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
S. epidermidis (26) | 2* | SEP1 | + | + | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
24 | SEP2 | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
S. equorum (17) | 2 | SEQ1 | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
3 | SEQ2 | − | NT | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | |
1 | SEQ3 | − | NT | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |
11 | SEQ4 | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
S. fleurettii (2) | 2 | SFL1 | − | NT | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
S. gallinarum (21) | 14 | SGA1 | − | NT | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
2 | SGA2 | − | NT | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | |
5 | SGA3 | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
S. haemolyticus (29) | 1 | SHA1 | − | NT | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
28 | SHA2 | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
S. hominis (11) | 11 | SHO | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
S. hyicus (3) | 1 | SHY1 | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
2 | SHY2 | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
S. kloosii (1) | 1 | SKL | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
S. nepalensis (2) | 2 | SNE | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
S. pasteuri (6) | 1 | SPA1 | + | + | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
5 | SPA2 | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
S. saprophyticus (16) | 1 | SSA1 | − | NT | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
1 | SSA2 | + | − | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
14 | SSA2 | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
S. sciuri (30) | 3 | SSC1 | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
1 | SSC2 | + | − | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |
1 | SSC3 | + | − | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | |
1 | SSC4 | + | − | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | |
1 | SSC4 | − | NT | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | |
6 | SSC5 | + (6) | − | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
17 | SSC6 | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
S. simulans (42) | 19 | SSI1 | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
1 | SSI2 | − | NT | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | |
1* | SSI3 | + | − | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | |
1* | SSI4 | + | − | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 2 | |
3 | SSI5 | + | + | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | |
2 | SSI6 | + | + | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | |
1 | SSI7 | + | − | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
14 | SSI8 | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
S. succinus (15) | 1 | SSU1 | − | NT | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
14 | SSU2 | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
S. vitulinus (6) | 1 | SVI1 | − | NT | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
5 | SVI2 | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
S. warneri (19) | 5 | SWA1 | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
1 | SWA2 | + | − | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
13 | SWA3 | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
S. xylosus (28) | 8 | SXY1 | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
1* | SXY2 | + | + | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | |
19 | SXY3 | − | NT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An asterisk indicates inhibitory activity was achieved with the chloroform-extracted product and inhibition was suppressed with the addition of proteinase K.
NT, not tested.