Table 3.
Predictors of poor outcomes in patients with bacteraemia*
| Predictor, n (total N=59)* | Outcome
|
OR (95% CI) | p-value | |
|---|---|---|---|---|
| Unimproved or died, n (%) | Improved, n (%) | |||
| Incorrect empirical antibiotics (N=36) | 17 (47.2) | 19 (52.8) | 8.05 (1.62 – 39.91) | 0.004 |
| Correct empirical antibiotics (N=20) | 2 (10.0) | 18 (90.0) | 0.12 (0.03 – 0.62) | 0.004 |
| HIV+ (N=45) | 11 (24.4) | 34 (75.6) | 0.75 (0.17 – 3.43) | 0.99 |
| HIV− (N=10) | 3 (30.0) | 7 (70.0) | 1.32 (0.29 – 6.02) | 0.99 |
| HIV+ on ARVs (N=21) | 6 (28.6) | 15 (71.4) | 0.74 (0.20 – 2.78) | 0.74 |
| HIV+ not on ARVs (N=20) | 7 (35.0) | 13 (65.0) | 1.34 (0.36 – 5.04) | 0.74 |
| SBP ≤90 mmHg (N=10) | 6 (60.0) | 4 (40.0) | 2.0 (0.46 – 8.70) | 0.29 |
| SBP >90 mmHg (N=38) | 12 (31.6) | 26 (68.4) | 0.5 (0.115 – 2.17) | 0.29 |
| SIRS (N=40) | 10 (25.0) | 30 (75.0) | 0.67(0.14 – 3.17) | 0.68 |
| No SIRS (N=9) | 3 (33.3) | 6 (66.7) | 1.5 (0.32 – 7.14) | 0.68 |
| Salmonella bacteraemia (N=10) | 2 (20.0) | 8 (80.0) | 0.43 (0.08 – 2.25) | 0.47 |
| Non-Salmonella bacteraemia (N=46) | 17 (37.0) | 29 (63.0) | 2.34 (0.45 – 12.34) | 0.47 |
| S. aureus bacteraemia (N=17) | 6(35.3) | 11 (64.7) | 1.09 (0.33 – 3.61) | 1.0 |
| Non-S. aureus bacteraemia (N=39) | 13 (33.3) | 26 (66.7) | 0.92 (0.28 – 3.03) | 1.0 |
SBP = systolic blood pressure; SIRS = systemic inflammatory response syndrome.
*
Cases of fungaemia (n=4) as opposed to bacteraemia were excluded from this analysis. Owing to missing data (5% of outcomes data, <5% of other variables), n for each characteristic does not add up to total N.