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. Author manuscript; available in PMC: 2017 Aug 18.
Published in final edited form as: S Afr Med J. 2015 Apr 8;105(5):370–374. doi: 10.7196/SAMJ.8780

Table 4.

Spectrum of antibiotic combinations available at MCH against bacteraemia isolates

Antibiotic regimen % covered Uncovered organisms
CTX alone 66 MRSA, ESBL GNRs
CTX + GEN 76 MRSA
CTX + CIP 75 MRSA* CIP-resistant GNRs
CTX + GEN + CIP 81 MRSA* CIP-resistant GNRs
VAN+CTX 83 ESBL GNRs
VAN+GEN 83 Salmonella
VAN+GEN + CIP 98 CIP-resistant Salmonella
VAN + IPM 100 None
IPM alone 85 MRSA

CTX = ceftriaxone; GEN = gentamicin; CIP = ciprofloxacin; VAN = vancomycin; IPM = imipenem.

*

Several MRSA isolates in this study showed in vitro susceptibility to CIP, although caution is necessary in using CIP to treat S. aureus infections as resistance is known to occur rapidly.