Figure 1.
Cacna1c heterozygous mice display antidepressant-like behavior. (a, b) Cacna1c HET mice show significantly higher sucrose preference (a) and sucrose consumption (b) compared with WT mice in the sucrose preference test (WT n=12, HET n=12). (c, d) HET mice spend significantly less time immobile than WT mice in the forced swim test (c) and the tail suspension test (d) (FST: WT n=14, HET n=9; TST: WT n=8, HET n=9). (e) HET mice travel similar distance as WT mice in the basal locomotor activity test (WT n=12, HET n=10). *p<0.05, **p<0.01 vs WT. Error bars are mean±SEM.