Table 4.

Characteristics of ROC curves based on panel 1 and panel 2, for the discovery and validation cohorts

Model	AUC	Sensitivity	Specificity	PPV	NPV
Panel 1: Control vs IBD (5 proteins)
Discovery	1.00 (0.99 to 1.0)	1.0 (0.83 to 1.0)	0.93 (0.78 to 0.99)	0.91	1.0
Validation	0.99 (0.99 to 1.0)	0.95 (0.75 to 1.0)	0.97 (0.83 to 1.0)	0.95	0.97
Panel 2: CD vs UC (12 proteins)
Discovery	0.95 (0.86 to 1.0)	1.0 (0.78 to 1.0)	0.933 (0.68 to 1.0)	0.94	1.0
Validation	0.86 (0.72 to 1.0)	0.73 (0.45 to 0.92)	0.87 (0.59 to 0.98)	0.85	0.76

CD, Crohn's disease; NPV, negative predictive value; PPV, positive predictive value; ROC, receiving operating characteristics.