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Predictions of the change in cellular current densities due to SCN5A mutations associated with Brugada syndrome
| Mutation | Fraction of current density reduction as compared with wild-type |
1 - Prediction score | |
|---|---|---|---|
|
| |||
| MutPred | MutPred2 | ||
| p.Arg620His | 1.00 | 0.64 | 0.93 |
| p.Arg811His | 0.57 | 0.14 | 0.22 |
| p.Ser1218Ile | 0.00 | 0.12 | 0.07 |
