. Author manuscript; available in PMC: 2018 Sep 1.

Published in final edited form as: Magn Reson Med. 2017 Jul 16;78(3):1100–1109. doi: 10.1002/mrm.26820

Table 2.

Differences between APTw and MTR Values for IDH-wildtype and IDH-mutant Gliomas

Parameters	IDH wild-type (n = 7)	IDH mutant (n = 20)	P values
APTw multi-ROI analysis:
Maximum	2.03±0.72	0.99±0.33	<0.001
Minimum	0.99±0.47	0.59±0.32	0.02
Whole-tumor APTw histogram analysis:
Mean	1.39±0.49	0.93±0.44	0.03
Variance	0.61±0.36	0.97±0.73	0.23
Skewness	−0.13±0.28	−0.35±0.83	0.50
Kurtosis	0.57±0.67	1.82±3.32	0.34
Slope	2.27±0.77	2.65±0.91	0.33
10^th percentile	0.48±0.54	−0.14±0.76	0.06
50^th percentile	1.39±0.46	0.96±0.36	0.02
90^th percentile	2.30±0.64	1.98±0.49	0.18
Peak	1.33±0.52	1.02±0.37	0.09
Whole-tumor MTR:
Mean	14.9±2.1	16.3±5.3	0.63

Note: Data are mean ±standard deviation. Significant results are printed in bold.