Table 2.
Details of composition of multivitamin and mineral supplements given in each trial
| Details | Daily intake of supplements |
|---|---|
| Study (location) | |
| Chavance et al 1993 (France)21 | Vitamins A (retinol 5000 IU), B1 (thiamine) 2.25 mg, B2 (riboflavin) 2.6 mg, B6 (pyridoxine) 3 mg, B12 (cyanocobalamin) 9 μg, C 90 mg, D2 400 IU, E 30 IU, nicotinamid 20 mg, biotin 45 μg, pantothenic acid 10 mg |
| Calcium 162 mg, iron 27 mg, zinc 22.5 mg, folic acid 0.4 mg, phosphorus 125 mg, iodine 150 μg, magnesium 100 mg, copper 3 mg, manganese 7.5 mg, potassium 7.5 mg | |
| Girodon et al 1999 (France)22 | Vitamins A (β carotene 6 mg), C 120 mg, E 15 mg Zinc 20 mg, selenium 100 μg |
| Chandra 1992 (United States)23 | Vitamins A (retinol 400 μg), B1 (thiamine) 2.2 mg, B2 (riboflavin) 1.5 mg, niacin 16 mg, B6 (pyridoxine) 3.0 mg, B12 4.0 μg, C 80 mg, D 4 μg, E 44 mg, Calcium 200 mg, iron 16 mg, zinc 14 mg, folate 400 μg, copper 1.4 mg, selenium 20 μg, iodine 0.2 mg, magnesium 100 mg. |
| Barringer et al 2003 (United States)24 | Vitamin A 4000 IU (β carotene 1000 IU), B1 (thiamine) 4.5 mg, B2 (riboflavin) 3.4 mg, niacin 20 mg, B6 (pyridoxine) 6 mg, B12 (cyanocobalamin) 30 μg, C (ascorbic acid) 120 mg, D 400 IU, E 60 IU, K 20 μg, biotin 0.03 mg, pantothenic acid 15 mg |
| Calcium 120 mg, iron 16 mg, folic acid 400 μg, zinc 22.5 mg, selenium 105 μg, magnesium 100 mg, copper 2 mg, iodine 150 μg, manganese 4 mg, chromium 180 μg | |
| Graat et al 2002, (Netherlands)25 | A capsule contained: Vitamins A (retinol 600 μg, β carotene 1.2 mg), B1 (thiamine) 1.4 mg, B2 (riboflavin) 1.6 mg, niacin 18 mg, B6 (pyridoxine) 2.0 mg, B12 (cyanocobalamin) 1 μg, biotin 150 μg, C 60 mg, E 10 mg, D (cholecalciferol) 5 μg, K 30 μg, pantothenic acid 6 mg |
| Calcium 74 mg, iron 4.0 mg, folic acid 200 μg, zinc 10 mg, selenium 25 μg, magnesium 30 mg, copper 1.0 mg, iodine 100 μg, phosphorus 49 mg, manganese 1.0 mg, chromium 25 μg, molybdenum 25 μg, silicium 2 μg | |
| Each participant received 2 capsules per day | |
| Chandra 2002 (location not specified)26 | Vitamins A (retinol 400 μg), B1 (thiamine) 2.2 mg, B2 (riboflavin) 1.5 mg, niacin 16 mg, B6 (pyridoxine) 3.0 mg, B12 4.0 μg, C 80 mg, D 4.0 μg, E 44 mg |
| Calcium 200 mg, iron 16 mg, zinc 14 mg, copper 1.4 mg, selenium 20 μg, iodine 200 μg, magnesium 100 mg, folate 400 μg | |
| Jain 2002 (India)27 | Vitamins A (retinol 400 μg), B1 (thiamine) 2.2 mg, B2 (riboflavin) 1.5 mg, niacin 16 mg, B6 (pyridoxine) 3.0 mg, B12 4.0 μg, E 44 mg |
| Calcium 200 mg, iron 16 mg, zinc 14 mg, copper 1.4 mg, selenium 20 μg, iodine 200 μg, magnesium 100 mg, folate 400 μg | |
| Girodon et al 1997 (France)28 | Vitamins A (β carotene 6 mg), C 120 mg, E 15 mg Zinc 20 mg, selenium 100 μg |
| Recommended daily allowances in the United Kingdom | |
| Men ≥5031,32 | Vitamins A 700 μg, B1 (thiamine) 0.9 mg, B2 (riboflavin) 1.3 mg, niacin 16 mg, B6 (pyridoxine) 1.4 mg, B12 1.5 μg, C 40 mg, D 10 μg (after age 65), E 10 mg |
| Calcium 700 mg, iron 8.7 mg, zinc 9.5 mg, selenium 75 μg, phosphorus 550 mg, magnesium 300 mg, copper 1.2 mg, iodine 140 μg | |
| Women ≥5031,32 | Vitamins A 600 μg, B1 (thiamine) 0.8 mg, B2 (riboflavin) 1.1 mg, niacin 12 mg, B6 (pyridoxine) 1.2 mg, B12 1.5 μg, C 40 mg, D 10 μg (after age 65), E 10 mg |
| Calcium 700 mg, iron 8.7 mg, zinc 7.0 mg, selenium 60 μg, phosphorus 550 mg, magnesium 270 mg, copper 1.2 mg, iodine 140 μg |